Cannabinoids and Epilepsy
نویسندگان
چکیده
منابع مشابه
Cannabinoids for epilepsy.
BACKGROUND Marijuana appears to have anti-epileptic effects in animals. It is not currently known if it is effective in patients with epilepsy. Some states in the United States of America have explicitly approved its use for epilepsy. OBJECTIVES To assess the efficacy of marijuana, or one of marijuana's constituents in the treatment of people with epilepsy. SEARCH METHODS We searched the Co...
متن کاملSlim evidence for cannabinoids for epilepsy.
Commentary Most practitioners who treat epilepsy will encounter patients using marijuana (Cannabis sativa) as alternative therapy. Anecdotal evidence of its efficacy against seizures is com-mon—in one study of an epilepsy center, 21% admitted using marijuana in the prior year, with the majority of these individuals feeling that it benefited seizure control (1). However, other patients may repor...
متن کاملCannabinoids in the Treatment of Epilepsy.
Despite the availability of more than 20 different antiseizure drugs and the provision of appropriate medical therapy, 30% of people with epilepsy continue to have seizures.1,2 The approval of many new antiseizure drugs during the past two decades, including several with novel mechanisms of action, has not substantially reduced the proportion of patients with medically refractory disease.1 The ...
متن کاملCannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?
The interest in cannabis-based products for the treatment of refractory epilepsy has skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ(9) - tetrahydrocannabinol (THC), utilized primarily for recreational purposes, are generally unsuitable for this indication, primarily because THC is associated with many undesired effects. Compared with THC, cannabidiol (...
متن کاملCannabinoids for pediatric epilepsy? Up in smoke or real science?
Public interest in the use of "medical marijuana" for the treatment of childhood epilepsy has burgeoned in the last few years. This has occurred in parallel with a growing interest in "medical marijuana" in general. Physicians and pediatricians must balance their patients' desire for immediate access to these products with the tenets of evidence-based medicine. This review discusses the biochem...
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ژورنال
عنوان ژورنال: Neurotherapeutics
سال: 2015
ISSN: 1933-7213,1878-7479
DOI: 10.1007/s13311-015-0375-5